Dr. Paul Bowyer
Senior Lecturer
Research Focus
Discovering the genetic basis of susceptibility to fungal disease in humans using whole exome sequencing of populations with defined disease phenotypes and controls and the genomics of pathogenicity and drug resistance in the human fungal pathogen Aspergillus fumigatus
Scientific Activities
Closely working with clinicians at UHSM in order to define clinical phenotypes, identify patients and obtain consent to take samples then analyse the samples in the laboratory. Extensive collaborations with sequencing centres in the UK(EBI) the USA (JCVI) and in Barcelona (CNAG) as well as with Aspergillus researchers worldwide.
Bioinformatic analysis of large exome sequence data sets, RNAseq data, genome assembly and comparison of fungal genomes, use of next gen sequencing for bespoke fitness and population studies, microbiome determination and metagenomics of pathogens. Gene manipulation in fungi and human cells.
Significant Publications
Collaborators
Dr. Elaine Bignell PhD
Reader in Applied Mycology and deputy Director of Manchester Fungal Infection Group
More about Dr. Elaine Bignell...Dr. Riina Richardson DDS, PhD, FRCPath, PGCertMedEd
Senior Lecturer
More about Dr. Riina Richardson...Dr. Michael Bromley
Senior Lecturer
More about Dr. Michael Bromley...Dr. Lily Novak Frazer
Lecturer in Medical Mycology, University of Manchester
More about Dr. Lily Novak Frazer...
