Dr. Laurence Bindschedler

Senior Lecturer in Plant Biochemistry

Research Focus

Understanding Molecular interactions during infection by biotrophic pathogenic fungi in cereals, using molecular, mass spectrometry tools, with particular focus on cereal powdery mildews. Proteomics analysis during plant pathogens interactions and other (a)biotic stresses

Scientific Activities

-Proteomic analysis of barley powdery mildew infective structures.

-Investigating the mode of action of effectors or virulence factors of barley powdery mildew using proteomics to understand protein-protein interactions between effectors and their plant targets.

-Devising alternative molecular tools based on RNAi for functional genomic and crop disease control of biotrophs and other wheat pathogens.

-Developing and adapting quantitative proteomics methods for the study of pathogenic fungi and their plant host.

-Supervision of PhD students and MRes students on topics related to above.

Significant Publications

Pennington HG, Gheorghe DM, Damerum A, Pliego C, Spanu PD, Cramer R, Bindschedler LV*, 2016. Interactions between the powdery mildew effector BEC1054 and barley proteins identify candidate host targets. J Proteome Research 15: 826-839.

Bindschedler LV, McGuffin LJ, Burgis TA, Spanu PD, Cramer R. 2011. Proteogenomics and in silico structural and functional annotation of the barley powdery mildew Blumeria graminis f. sp. hordei. Methods. 54: 432-41.

Bindschedler LV, Palmblad M, Cramer R. 2008. Hydroponic isotope labelling of entire plants (HILEP) for quantitative plant proteomics. Phytochemistry 69:1962-72.


Contact information

Royal Holloway University of London
TW20 0EX

Email: Laurence.Bindschedler@rhul.ac.uk