Directional growth of fungal pathogens
My research primarily focuses on how the hyphae of human fungal pathogens grow and steer during invasive fungal disease and in medical biofilms. I also work on the biosynthetic pathway of myriocin, a fungal metabolite and potent immunosuppressant.
Thomson DD, Wehmeier SW, FitzRoy J, Janmey P, Caballero-Lima D, Crossley A & Brand AC (2015) ‘Contact-induced apical asymmetry drives the thigmotropic responses of Candida albicans hyphae.’ Cellular Microbiology 17:342-54.
Brand AC, Morrison E, Milne S, Gonia S, Gale CA & Gow NAR (2014) ‘Cdc42 GTPase dynamics control directional growth responses.’ Proceedings of the National Academy of Sciences USA 111:811-6.
Brand AC (2012) ‘Hyphal growth in human fungal pathogens and its role in virulence’, Journal of International Microbiology, 2012;2012:517529.
MRC Centre for Medical Mycology
University of Aberdeen
Institute of Medical Sciences
Phone: +44 (0)1224 437495