Dr. Alexandra Brand PhD, FRSB

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Research Focus

Directional growth of fungal pathogens

Scientific Activities

My research primarily focuses on how the hyphae of human fungal pathogens grow and steer during invasive fungal disease and in medical biofilms. I also work on the biosynthetic pathway of myriocin, a fungal metabolite and potent immunosuppressant.

Significant Publications

Thomson DD, Wehmeier SW, FitzRoy J, Janmey P, Caballero-Lima D, Crossley A & Brand AC (2015) ‘Contact-induced apical asymmetry drives the thigmotropic responses of Candida albicans hyphae.’ Cellular Microbiology 17:342-54.

Brand AC, Morrison E, Milne S, Gonia S, Gale CA & Gow NAR (2014) ‘Cdc42 GTPase dynamics control directional growth responses.’ Proceedings of the National Academy of Sciences USA 111:811-6.

Brand AC (2012) ‘Hyphal growth in human fungal pathogens and its role in virulence’, Journal of International Microbiology, 2012;2012:517529.


Collaborators

Contact information

MRC Centre for Medical Mycology
University of Aberdeen
Institute of Medical Sciences
Aberdeen
AB25 2ZD

Email: a.brand@abdn.ac.uk
Phone: +44 (0)1224 437495

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